Li, Mei-Hui


Mei-Hui Li



Office : Room 603, Department of Geography

Email :

Phone : 886-2-33665839

Website : Environmental Ecology Lab



My teaching and research interests span several broad and diverse areas including environmental toxicology, medical and health geography and environmental ecology. Much of my research, funded under a series of National Science Council projects, has been on the effects of endocrine disruptors. I am currently also involved in work on the ecological effects of urbanization. I also have an interest in medical geography. The diverse nature of my research is reflected in my training, as I have degrees in Geography (BS), Zoology (MS) and Environmental Toxicology (Ph. D).

Research interests: environmental toxicology and biological monitoring, ecological effects of urbanization, river ecosystem health



More specific details of my research areas are as follows:

  1.  Persistent organic pollutants and emerging contaminants
    I am interested in a wide range of issues associated with the toxic effects of persistent organic pollutants, including hepatic inductions and endocrine effects of polychlorinated biphenols; hepatic inductions and reproductive effects of polybrominated diphenyl ether; the toxic effects of nonylphenol on aquatic animals, and the toxic effects of perfluorooctanoic acid on aquatic animals. To this end I have developed the Environmental Toxicology Laboratory at the Department of Geography, which has become a cutting-edge facility in Taiwan.
  2. Bioindicators and environmental monitoring
    I have a strong interest in the use of bioindicators for environmental monitoring in Taiwan. More specific interests include: the application of developmental instability of crabs to coastal pollution; antioxidant enzyme induction of plants to air pollution; vitellogenin induction of male fish and endocrine disruptors.
  3. Issues in environmental ecology
    I am also interested in how human activities or disturbance affect animal survival and distribution in Taiwan, such as urbanization effects on animal survival and distribution; impacts of land use changes on biodiversity.
  4. Human health and the environment
    I am very interested in understanding the relationship between human health and global environmental change, especially the health effects of persistent organic pollutants. I also have strong interests in various other aspects of medical geography, including climate change and human health; emerging and re-emerging infectious diseases; and geographic diffusion of disease.



Ph.D. University of Illinois, Urbana, USA (1996)

M.S. Southern Illinois University, Carbondale, USA (1991)

B.S. National Taiwan University, Taipei, Taiwan (1987)



Environmental Ecology

Urban Ecology and Environment

Ecological Issues in a Changing World

Critical Physical Geography

Introduction to Ecological Monitoring

Environmental Change and Disease

Environmental Toxicology



AuthorDate of PublicationTitleSource
Li, M.H. 2023 Double exposure framework of COVID-19 pandemic and climate change. In: Akhtar, R. (eds) Climate Change and Human Health Scenarios: International Case Studies. pp. 49-65. Springer Nature Switzerland.
Li, M.H., Wu, IH. 2022 Analysis of 2021 COVID-19 Outbreak and Vaccination in Taiwan Using a Causal Loop Diagram Approach In: Akhtar, R. (eds) Coronavirus (COVID-19) Outbreaks, Vaccination, Politics and Society. pp. 83-97. Springer, Cham.
Solà, E., Leria, L., Stocchino, G.A., Bagherzadeh, R., Balke, M., Daniels, S.R., Harrath, A.H., Khang, T.F., Krailas, D., Kumar, B., Li, M.H., Maghsoudlou, A., Matsumoto, M., Naser, N., Oben, B., Segev, O., Thielicke, M., Tong, X., Zivanovic, G., Manconi, R., Baguñà, J., Riutort, M. 2022 Three dispersal routes out of Africa: The puzzling biogeographical history of Dugesia freshwater planarians. Journal of Biogeography
Li, M.H. 2021-05 Proactive strategies, social innovation, and community engagement in relation to COVID-19 in Taiwan Coronavirus (COVID-19) Outbreaks, Environment and Human Behaviour
Li, Y.J. Li, M.-H. Shih, Y.-H. 2020- Aerobic degradation and the effect of hexabromocyclododecane by soil microbial communities in Taiwan Environment International
Li, M.H. 2020- Applying a social–ecological framework to Yucheng: 40 years after exposure to polychlorinated biphenyls and dibenzofurans Archives of Environmental & Occupational Health
Li, M.H. 2020- Enzymatic biomarker responses in freshwater planarians exposed to endocrine disruptors. Fresenius Environment Bulletin
Li, M.H. 2020- Planarian mobility assay as a simple alternative for rapid screening aquatic acute toxicity of personal care products. Fresenius Environment Bulletin
Hung, L.-S. and Li, M.-H 2020- Extreme weather events and health responses in Taiwan. Extreme Weather Events and Human Health: International Case Studies.
Li, M.-H 2019-02 Comparative toxicities of 10 widely used biocides in three freshwater invertebrate species. Chemistry and Ecology
Chien, W.-C., Li, M.-H.*, Li, H.-J. 2019- Appropriate management practices help enhance odonate species richness of small ponds in peri-urban landscapes. Urban Ecosystem
Wu, J.-P., Li, M.-H 2018-08 Use of freshwater planarians in environmental toxicology studies: Advantages and potential. Ecotoxicology and Environmental Safety
Mei-Hui Li 2017-12 Trends and seasonal variations of climate, air quality, and mortality in three major cities in Taiwan. Climate Change and Air Pollution: The impact on the human health in developed and developing countries
Wu, J.-P., Li, M.-H 2017-02 Low uptakes of Cd, Cu, and Zn in Dugesia japonica, a freshwater planarian with higher tolerance to metals. Chemistry and Ecology
Li, Mei-Hui 2016-08 Development of in vivo metabolic enzyme assays for ecotoxicity screening: In vivo measurement of phases I and II enzyme activities in freshwater planarians Ecotoxicology and Environmental Safety
Tzai-Hung Wen, Min-Hau Lin, and Mei-Hui Li 2016-06 Potential effects of climate changes on dengue transmission- Review of empirical evidences from Taiwan. Climate Change and Human Health Scenario in South and Southeast Asia
Jui-Pin Wu, Mei-Hui Li, Jhih-Sheng Chen, Szu-Yao Chung, Hui-Ling Lee 2015-03 Disturbances to neurotransmitter levels and their metabolic enzyme activity in a freshwater planarian exposed to cadmium Neurotoxicology
Jui-Pin Wu, Mei-Hui Li 2015-03 Inhibitory effects of pain relief drugs on neurological enzymes: implications on their potential neurotoxicity to aquatic animals. Environmental Toxicology and Pharmacology
Mei-Hui Li 2014-12 Effects of bisphenol A, two synthetic and a natural estrogens on head regeneration of the freshwater planarians, Dugesia japonica. Toxicological and Environmental Chemistry
Jui-Pin Wu, Hui-Ling Lee & Mei-Hui Li 2014-11 Cadmium neurotoxicity on a freshwater planarian Archives of Environmental Contamination and Toxicology
Li, M.-H. 2013-12 Acute toxicity of thirty pharmaceutically active compounds to freshwater planarians, Dugesia japonica Toxicological and Environmental Chemistry
Li, M.-H. 2013-09 Acute toxicity of industrial endocrine-disrupting chemicals, natural and synthetic sex hormones to the freshwater planarians, Dugesia japonica Toxicological and Environmental Chemistry
Tseng, L.-H., Hsu, P.-C., Lee, C.-W., Tsai, S.-S., Pan, M.-H., Li, M.-H. 2013-07 Developmental exposure to decabrominated diphenyl ether (BDE-209): effects on sperm oxidative stress and chromatin DNA damage in mouse offspring Environmental Toxicology
Lee,T.-H. and Li, M.-H. 2013- Intertidal assemblages on artificial structures and natural rocky habitats on Taiwan’s north coast Raffles Bulletin of Zoology
李美慧 2013- 都市化河川水質時空變化-以基隆河為例 環境與世界
Wu, J.-P., Chen, H.-C., and Li, M.-H. 2012-08 Bioaccumulation and toxicodynamics of cadmium in the freshwater planarian and the protective effects of N-acetylcysteine Archives of Environmental Contamination & Toxicology
Wu, J.-P., Li, M.-H. Chen, J.-S., and Lee, H.-L. 2012-06 In vivo and in vitro metabolism of tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by freshwater planarian, Dugesia japonica Chemosphere
Li, M.-H. 2012-04 Survival, mobility, and membrane-bound enzyme activities of freshwater planarians, Dugesia japonica, exposed to synthetic and natural surfactants Environmental Toxicology and Chemistry
Li, M.-H. 2012-01 Acute toxicity of benzophenone-type UV filters and paraben preservatives to freshwater planarians, Dugesia japonica Toxicological and Environmental Chemistry
李宗翰,李美慧* 2012- 遊客踩踏行為對岩岸潮間帶附著生物的影響 戶外遊憩研究
Li, M.-H.* 2011- Changes of cholinesterase and carboxylesterase activities in male guppies (Poecilia reticulate), after exposure to ammonium perfluorooctanoate, but not perfluorooctane sulfonate Fresenius Environmental Bulletin
Wu, J.-P., Chen, H.-C., Li, M.-H.* 2011- The preferential accumulation of cadmium in the head portion of the freshwater planarian, Dugesia japonica (Platyhelminthes: Turbellaria) Metallomics
Li, M.-H.* 2010- Chronic effects of perfluorooctane sulfonate and ammonium perfluorooctanoate on biochemical parameters, survival and reproduction of Daphnia magna Journal of Health Science
李美慧 2009- An Overview of Environmental Health Status and Related Studies in Taiwan 中國地理學會會刊Bulletin of the Geographical Society of China
Lin, C.W.,Li, M.-H.* 2009- Effects of two types of landfills on river water quality and endocrine disruptor concentrations before and after rainfall in a subtropical climate Water Quality Research Journal of Canada
Li, M.-H.* 2009- Toxicity of perfluorooctane sulfonate and perfluorooctanoic acid to plants and aquatic invertebrates Environmental Toxicology
Tseng, L.-H., Li, M.-H. Tsai, S.-S., Lee, C.W., Pan, M.-H., Yao, W.-J., Hsu, P.-C. 2008- Developmental exposure to decabromodiphenyl ether (PBDE 209): Effects on thyroid hormone and hepatic enzyme activity in male mouse offspring. Chemosphere
Li, M.-H. 2008- Effects of nonionic and ionic surfactants on survival, oxidative stress, and cholinesterase activity of planarian Chemosphere
Li, M.-H. 2008- Effects of nonylphenol on cholinesterase and carboxylesterase activities in male guppies (Poecilia reticulata). Ecotoxicology and Environmental Safety
Hong, L. and Li, M.-H.* 2007-06 Acute toxicity of nonylphenol to aquatic invertebrates in Taiwan Bulletin of Environmental Contamination & Toxicology
李美慧 2005-01 Effect of nonylphenol on plasma vitellogenin of male adult guppies (Poecilia reticulata). Environmental Toxicology
李美慧, 2. Hsu, P.-C., Guo, Y.L., and Li, M.-H.* 2004- Effects of postnatal exposure to 3,3’,4,4’- tetrachlorobiphenyl on sperm function and hormone levels in adult rats. Chemosphere
李美慧 2004- Morphological biomarkers of shore crabs (Grapsus albolineatus) living in the vicinity of a coastal landfill site. Fresenius Environmental Bulletin
李美慧 2003- Peroxidase and superoxide dismutase activities in fig leaves in response to ambient air pollution in a subtropical city Archives of Environmental Contamination & Toxicology


Fiscal YearPlan NameTitle
111 台灣昆蟲復育-以混合地理學與批判自然地理學之視角 計畫主持人
107 全球生物均質化及東南亞和南亞都市生物多樣性之探討 計畫主持人
106 評估日常用品及農業藥品中常見抗菌劑的水生毒性與生態影響 計畫主持人
103 評估淡水渦蟲做為生態毒性測試模式之可行性 計畫主持人
102 利用淡水渦蟲檢驗水中新興污染物 計畫主持人
101 淡水河生態系生態功能及其生態服務價值評估--淡水河河川水質之生態系功能及生態系服務評估研究(II) 計畫主持人
101 大陸型與島嶼型流域氮遺失之觀測與模擬 共同主持人
100 利用淡水渦蟲檢驗水中新興污染物 計畫主持人
100 利用淡水渦蟲檢驗水中新興污染物 計畫主持人
100 淡水河生態系之服務機制、價值評估及效益移轉--淡水河的生態系統碳通量(I) 共同主持人
099 利用渦蟲做為檢測界面活性劑對水生動物毒性之測試系統 計畫主持人
098 利用渦蟲做為檢測界面活性劑對水生動物毒性之測試系統 計畫主持人
097 利用渦蟲做為檢測界面活性劑對水生動物毒性之測試系統 計畫主持人
097 利用渦蟲做為檢測界面活性劑對水生動物毒性之測試系統 計畫主持人
096 全氟辛烷磺酸對水生動物之影響 計畫主持人
095 全氟辛烷磺酸對水生動物之影響 計畫主持人
094 利用孔雀魚檢測環境雄性激素 計畫主持人
093 空氣污染與榕樹葉片過氧化酵素活性及發育不穩定性之探討 計畫主持人
091 台灣山坡地環境敏感區土地利用變遷及其對環境衝擊之研究--總計畫暨子計畫五:濁水溪流域土地利用變遷機制研究--陳有 蘭溪集水區山坡地土地經營面向分析(II) 共同主持人
091 利用雄孔雀魚評估環境雌性激素之影響 計畫主持人
090 台灣山坡地與海岸環境敏感區土地利用變遷及其對環境衝擊之研究--子計畫二:土地利用變遷與河川污染之研究(I) 計畫主持人
089 發展整合型的母幼鼠急性反映測試方法來檢測多氯聯苯之毒性(II) 計畫主持人
089 利用發育不穩定性來監測基隆附近海岸環境(II) 計畫主持人
089 發展整合型的母幼鼠急性反應測試方法來檢測多氯聯苯之毒性(1/3) 計畫主持人
088 利用發育不穩定性來監測基隆附近海岸環境 計畫主持人
086 生物監測法之綜合整理與討論 計畫主持人


2012 Excellent Publication Research Award, NTU, Taiwan

2010 Excellent Publication Research Award, NTU, Taiwan

2009 Distinguished Publication Research Award, NTU, Taiwan

2007 Distinguished Teaching Award (University), NTU, Taiwan

2006 Excellent Publication Research Award, NTU, Taiwan

2004 Outstanding Teaching Award (University), NTU, Taiwan