Li, Mei-Hui



  • BIOS







Mei-Hui Li



Office : Room 603, Department of Geography

Email : This email address is being protected from spambots. You need JavaScript enabled to view it.

Phone : 886-2-33665839

Website : Environmental Ecology Lab


My teaching and research interests span several broad and diverse areas including environmental toxicology, medical and health geography and environmental ecology. Much of my research, funded under a series of National Science Council projects, has been on the effects of endocrine disruptors. I am currently also involved in work on the ecological effects of urbanization. I also have an interest in medical geography. The diverse nature of my research is reflected in my training, as I have degrees in Geography (BS), Zoology (MS) and Environmental Toxicology (Ph. D).

Research interests: environmental toxicology and biological monitoring, ecological effects of urbanization, river ecosystem health


Ph.D. University of Illinois, Urbana, USA (1996)

M..S Southern Illinois University, Carbondale, USA (1991)

B.S. National Taiwan University, Taipei, Taiwan(1987)


More specific details of my research areas are as follows:

1. Persistent organic pollutants and emerging contaminants I am interested in a wide range of issues associated with the toxic effects of persistent organic pollutants, including hepatic inductions and endocrine effects of polychlorinated biphenols; hepatic inductions and reproductive effects of polybrominated diphenyl ether; the toxic effects of nonylphenol on aquatic animals, and the toxic effects of perfluorooctanoic acid on aquatic animals. To this end I have developed the Environmental Toxicology Laboratory at the Department of Geography, which has become a cutting-edge facility in Taiwan.

2. Bioindicators and environmental monitoring I have a strong interest in the use of bioindicators for environmental monitoring in Taiwan. More specific interests include: the application of developmental instability of crabs to coastal pollution; antioxidant enzyme induction of plants to air pollution; vitellogenin induction of male fish and endocrine disruptors.

3. Issues in environmental ecology I am also interested in how human activities or disturbance affect animal survival and distribution in Taiwan, such as urbanization effects on animal survival and distribution; impacts of land use changes on biodiversity.

4. Human health and the environment I am very interested in understanding the relationship between human health and global environmental change, especially the health effects of persistent organic pollutants. I also have strong interests in various other aspects of medical geography, including climate change and human health; emerging and re-emerging infectious diseases; and geographic diffusion of disease.


Environmental Ecology

Urban Ecology and Environment

Ecological Issues in a Changing World

Critical Physical Geography

Introduction to Ecological Monitoring

Environmental Change and Disease

Environmental Toxicology


Refereed Articles (2001-present):

Li, Y.J. Li, M.-H. Shih, Y.-H. (2020) Aerobic degradation and the effect of hexabromocyclododecane by soil microbial communities in Taiwan. Environment International 145:106128.

Li, M.-H. (2020) Applying a social–ecological framework to Yucheng: 40 years after exposure to polychlorinated biphenyls and dibenzofurans. Archives of Environmental & Occupational Health 75(5):395-405.

Li, M.-H. (2020) Planarian mobility assay as a simple alternative for rapid screening aquatic acute toxicity of personal care products. Fresenius Environment Bulletin 29(5):3362-3369.

Li, M.-H. (2020) Enzymatic biomarker responses in freshwater planarians exposed to endocrine disruptors. Fresenius Environment Bulletin 29(5):3354-3361.

Chien, W.-C., Li, M.-H.*, Li, Hsin-Ju.  (2019) Appropriate management practices help enhance odonate species richness of small ponds in peri-urban landscapes. Urban Ecosystem

Li, M.-H. (2019) Comparative toxicities of 10 widely used biocides in three freshwater invertebrate species. Chemistry and Ecology 35:472-482.

Wu, J.-P., Li, M.-H.* (2018) Use of freshwater planarians in environmental toxicology studies: Advantages and potential. Ecotoxicology and Environmental Safety 161:45-56.

Wu, J.-P., Li, M.-H (2017). Low uptakes of Cd, Cu, and Zn in Dugesia japonica, a freshwater planarian with higher tolerance to metals. Chemistry and Ecology, 33: 257-269. (SCI)

Li, M.-H. (2016) Development of in vivo metabolic enzyme assays for ecotoxicity screening: In vivo measurement of phases I and II enzyme activities in freshwater planarians. Ecotoxicology and Environmental Safety 130:19-28.

Wu, J.-P.; Li, M.-H. (2015) Inhibitory effects of pain relief drugs on neurological enzymes: implications on their potential neurotoxicity to aquatic animals, Environmental Toxicology and Pharmacology, 39, 898-905. (SCI)

Wu, J.-P.; Li, M.-H.; Chen, J.-S.; Lee, H.-L. (2015) Disturbances to neurotransmitter levels and their metabolic enzyme activity in a freshwater planarian exposed to cadmium, Neurotoxicology, 47, 72-81. (SCI)

Li, M.-H. (2014) Effects of bisphenol A, two synthetic and a natural estrogens on head regeneration of the freshwater planarians, Dugesia japonica. Toxicological and Environmental Chemistry, 96, 1174-1184. (SCI).

Wu, J.-P.; Lee, H.-L; Li, M.-H. (2014) Cadmium neurotoxicity on a freshwater planarian, Archives of Environmental Contamination and Toxicology, 67, 639-650. (SCI)

Li, M.-H. (2013) Spatial and Temporal Changes in Water Quality of an Urbanized River-A Case Study of Keelung River, Environment And Worlds, 27, 77-96.(in Chinese)

Li, M.-H. (2013) Acute toxicity of thirty pharmaceutically active compounds to freshwater planarians, Dugesia japonica, Toxicological and Environmental Chemistry, 95(7), 1157-1170. (SCI)

Li, M.-H. (2013) Acute toxicity of industrial endocrine-disrupting chemicals, natural and synthetic sex hormones to the freshwater planarians, Dugesia japonica, Toxicological and Environmental Chemistry, 95(6), 984-991. (SCI)

Tseng, L.-H.; Hsu, P.-C.; Lee, C.-W.; Tsai, S.-S.; Pan, M.-H.; Li, M,-H. (2013) Developmental exposure to decabrominated diphenyl ether (BDE-209): effects on sperm oxidative stress and chromatin DNA damage in mouse offspring, Environmental Toxicology, 28,380-390. (SCI)

Lee,T.-H.; Li, M.-H.* (2013) Intertidal assemblages on artificial structures and natural rocky habitats on Taiwan’s north coast, Raffles Bulletin of Zoology, 61, 331-342. (SCI)

Wu, J.-P.; Chen, H.-C.; Li, M,-H.* (2012) Bioaccumulation and toxicodynamics of cadmium in the freshwater planarian and the protective effects of N-acetylcysteine, Archives of Environmental Contamination and Toxicology, 63, 220-229. (SCI)

Wu, J.-P.; Li, M,-H.; Chen, J.-S.; Lee, H.-L. (2012) In vivo and in vitro metabolism of tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by freshwater planarian, Dugesia japonica, Chemosphere, 87, 1341-1347. (SCI)

Li, M,-H. (2012) Survival, mobility, and membrane-bound enzyme activities of freshwater planarians, Dugesia japonica, exposed to synthetic and natural surfactants, Environmental Toxicology and Chemistry, 31(4), 843-850. (SCI)

Li, M,-H. (2012) Acute toxicity of benzophenone-type UV filters and paraben preservatives to freshwater planarians, Dugesia japonica. Toxicological and Environmental Chemistry, 94(3), 566-573. (SCI)

Lee, T.-H.; Li, M,-H.* (2012) Effects of visitor trampling on the populations of attached organisms in intertidal rocky shore, Journal of Outdoor Recreation Study 25:1-24. (TSSCI) (in Chinese with English Abstract)

Wu, J.-P.; Chen, H.-C.; Li, M,-H.* (2011) The preferential accumulation of cadmium in the head portion of the freshwater planarian, Dugesia japonica (Platyhelminthes: Turbellaria). Metallomics, 3, 1368-1375. (SCI)

Li, M,-H. (2011) Changes of cholinesterase and carboxylesterase activities in male guppies (Poecilia reticulate), after exposure to ammonium perfluorooctanoate, but not perfluorooctane sulfonate, Fresenius Environmental Bulletin, 20, 2065-2070. (SCI)

Li, M,-H., 2010. Chronic effects of perfluorooctane sulfonate and ammonium perfluorooctanoate on biochemical parameters, survival and reproduction of Daphnia magna, Journal of Health Science, 56, 104-111. (SCI)

Lin, C.-W; Li, M,-H., 2009. Effects of two types of landfills on river water quality and endocrine disruptor concentrations before and after rainfall in a subtropical climate, Water Quality Research Journal of Canada, 44, 355-363. (SCI)

Li, M.-H., 2009. An overview of environmental health status and related studies in Taiwan, Bulletin of the Geographical Society of China, 42,1-24.

Li, M.-H., 2009. Toxicity of perfluorooctane sulfonate and perfluorooctanoic acid to plants and aquatic invertebrates, Environmental Toxicology, 24, 95-101. (SCI)

Li, M.-H., 2008. Effects of nonylphenol on cholinesterase and carboxylesterase activities in male guppies (Poecilia reticulata), Ecotoxicology and Environmental Safety, 71, 781-786. (SCI)

Li, M.-H. (2008) Effects of nonionic and ionic surfactants on survival, oxidative stress, and cholinesterase activity of planarian. Chemosphere 70:1796-1803. (SCI)

Tseng, L.-H.; Li, M.-H.; Tsai, S.-S.; Lee, C.W.; Pan, M.-H.; Yao, W.-J.; Hsu, P.-C., 2008. Developmental exposure to decabromodiphenyl ether (PBDE 209): effects on thyroid hormone and hepatic enzyme activity in male mouse offspring, Chemosphere, 70, 640-647. (SCI)

Hong, L.; Li, M.-H., 2007. Acute toxicity of nonylphenol to aquatic invertebrates in Taiwan. Bulletin of Environmental Contamination & Toxicology, 78, 445-449. (SCI)

Tseng, L.-H.; Lee, C.W.; Pan, M.-H.; Tsai, S.-S.; Li, M.-H.; Chen, J.-R.; Lay, J.-J.; Hsu, P.-C., 2006. Postnatal exposure of the male mouse to 2,2',3,3',4,4',5,5',6,6'- decabrominated diphenyl ether: decreased epididymal sperm functions without alterations in DNA content and histology in testis, Toxicology, 224, 33-43. (SCI)

Li, M.-H., 2005. A hot topic in medical geography – Studies of new infectious disease, Journal of Geographical Science, 41, 45-64. (TSSCI)

Li, M.-H.; Wang, Z.-R., 2005. Effect of nonylphenol on plasma vitellogenin of male adult guppies (Poecilia reticulata), Environmental Toxicology, 20, 53-59. (SCI)

Wang, Z.-R.; Li, M.-H., 2004. Effects of exogenous endocrine disruptors on fish reproduction, Chinese Bioscience, 47, 19-34. (in Chinese with English Abstract)

Li, M.-H., 2004. Morphological biomarkers of shore crabs (Grapsus albolineatus) living in the vicinity of a coastal landfill site. Fresenius Environmental Bulletin, 13, 485-490. (SCI)

Hsu, P.-C.; Guo, Y.L.; Li, M.-H., 2004. Effects of postnatal exposure to 3,3’,4,4’- tetrachlorobiphenyl on sperm function and hormone levels in adult rats, Chemosphere, 54, 611-618. (SCI)

Li, M.-H., 2003. Peroxidase and superoxide dismutase activities in fig leaves in response to ambient air pollution in a subtropical city. Archives of Environmental Contamination & Toxicology, 45, 168-176. (SCI)

Hsu, P.-C.; Li, M.-H.; Guo, Y.L., 2003. Postnatal exposure of 2,2’,3,3’,4,6’- hexachlorobiphenyl and 2,2’,3,4’,5’,6-hexachlorobiphenyl on sperm function and hormone levels in adult rats, Toxicology, 187, 117-126. (SCI)

Li, M.-H., 2002. Potential effects of endocrine disruptors on human health, Taiwan Journal of Public Health, 21, 305-320. (TSSCI) (in Chinese with English Abstract)

Li, M.-H., 2002. Fluctuating asymmetry and intersexuality in the shore crab Grapsus albolineatus near a coastal landfill site in northern Taiwan. Bulletin of Marine Science, 70, 75-88. (SCI)

Rose, R. L.; Khan, M.A.; Li, M.-H.; Gillette, J.S.; Hansen, L.G., 2002. Endocrine effects of episodic polychlorinated biphenyl (PCB) congeners, Review of Toxicology, 4, 161-178.

Li, M.-H., 2001. Shell disease and fluctuating asymmetry in shore crabs near a landfill at the coastal area of Keelung in Taiwan, Fresenius Environmental Bulletin, 10, 576-580. (SCI)

Li, M.-H.; Hsu, P.-C.; Guo, Y.L., 2001. Hepatic enzyme induction and acute endocrine effects of 2,2’,3,3’,4,6’-hexachlorobiphenyl and 2,2’,3,4’,5’,6 -hexachlorobiphenyl in prepubertal female rats, Archives of Environmental Contamination & Toxicology, 41, 381-385. (SCI)


Books & Book Chapters :

Li, M.-H. (2021) Proactive strategies, social innovation, and community engagement in relation to COVID-19 in Taiwan. Rais Akhtar (ed) Coronavirus (COVID-19) Outbreaks, Environment and Human Behaviour. Springer (ISBN 978-3-030-68120-3)

Hung, L.-S. and Li, M.-H. (2020) Extreme weather events and health responses in Taiwan. Rais Akhtar (ed) Extreme Weather Events and Human Health: International Case Studies. pp. 197-207. Springer. (ISBN 978-3-030-23773-8)

Li, M.-H. (2018) Trends and seasonal variations of climate, air quality, and mortality in three major cities in Taiwan. Rais Akhtar and Cosimo Palagiano (eds) Climate Change and Air Pollution: The impact on the human health in developed and developing countries. pp. 199-213. Springer. (ISBN 978-3-319-61345-1)

Li, M.-H. (2017) Emerging environmental problems and challenges in Taiwan. J.-C. and Chou, K.-T. (eds) Sustainable Development under Climate Change in Taiwan. pp. 93-111. National Taiwan University Press. (ISBN 978-986-05-0593-1) (in Chinese)

Wen, T.-H., Lin, M.-H., and Li, M.-H*. (2016) Potential effects of climate changes on dengue transmission- Review of empirical evidences from Taiwan. Rais Akhtar (ed) Climate Change and Human Health Scenario in South and Southeast Asia. pp. 269-281. Springer. (ISBN 978-3-319-23684-1)

Li, M.-H., 2010. Organophosphates. Encyclopedia of Geography. Barney Warf, editor in chief. Sage Publications. (Outstanding Reference Source" award at the American Library Association 2010 midwinter meeting, RUSA 2011 Outstanding Reference Sources Award Winner.)

Li, M.-H., 2010. Herbicide. Encyclopedia of Geography. Barney Warf, editor in chief. Sage Publications. (Outstanding Reference Source" award at the American Library Association 2010 midwinter meeting, RUSA 2011 Outstanding Reference Sources Award Winner.)

Li, M.-H., 2006. Introduction to Ecological Monitoring. Ming-Wen Publisher, Taipei. 278.



Li, M.-H., 2012. Precautionary principle, environmental hormone, and infant and children health. Science Development, 470, 58-63. (in Chinese)

Li, M.-H., 2009. Globalization of environmental pollution. Science Development, 440, 22-28. (in Chinese)


Development of freshwater planarian as a bioassay model for emerging pollutants, 100.08.01-102.07.31, NSC.

Use of planarians as a testing model to examine aquatic toxicity of surfactants, 97.08.01-100.07.31, NSC.

Effects of perfluorooctane sulfonic acid on aquatic animals II, 96.08.01~97.07.31, NSC.

Effects of perfluorooctane sulfonic acid on aquatic animals I, 95.08.01~96.07.31, NSC.

Use of guppies to detect environmental androgens, 94.08.01~95.07.31, NSC.



2012 Excellent Publication Research Award, NTU, Taiwan

2010 Excellent Publication Research Award, NTU, Taiwan

2009 Distinguished Publication Research Award, NTU, Taiwan

2007 Distinguished Teaching Award (University), NTU, Taiwan

2006 Excellent Publication Research Award, NTU, Taiwan

2004 Outstanding Teaching Award (University), NTU, Taiwan